Schwannoma vestibular: Experiência do Hospital de Egas Moniz entre 2007 e 2021

Autores

  • Pedro Branco Hospital Egas Moniz, Portugal https://orcid.org/0000-0003-3742-6542
  • Tiago Colaço Hospital Egas Moniz, Portugal
  • João Pedro Oliveira Hospital Egas Moniz, Portugal
  • Luís Castelhano Hospital Egas Moniz, Portugal
  • Filipe Correia Hospital Egas Moniz, Portugal
  • Sílvia Pereira Hospital Egas Moniz, Portugal
  • Luís Marques Hospital Egas Moniz, Portugal
  • Pedro Escada Hospital Egas Moniz, Portugal

DOI:

https://doi.org/10.34631/sporl.1045

Palavras-chave:

Neurinoma do acústico, Paralisia facial, Preservação da audição, Radiocirurgia, Estudos retrospetivos, Cirurgia, Espera vigilante, Schwannoma vestibular, Resultado do tratamento

Resumo

Objectivo: Reportar a experiência dum centro terciário na abordagem diagnóstica, decisão, terapêutica e seguimento dos doentes com schwannoma vestibular esporádico.

Material e Métodos: Estudo retrospetivo dos doentes com schwannoma vestibular esporádico, seguidos no Hospital Egas Moniz entre 2007 e 2021. Foram recolhidos os dados demográficos, clínicos, classificação dos tumores, decisão do tratamento e resultados de 79 doentes e analisados os seguintes outcomes: grau de resseção do tumor; perda auditiva; e grau de paralisia facial.

Resultados: 28% dos doentes operados tiveram uma resseção completa ou quase completa do tumor e 72% uma resseção subtotal. 7 em cada 8 doentes operados por via retrosigmoideia ficaram cofóticos, assim como 2 dos 3 doentes por via da fossa média. Não foi encontrada diferença na prevalência da paralisia facial entre as várias abordagens cirúrgicas.

Conclusão: Esta é uma das maiores séries reportadas a nível nacional. Os outcomes obtidos são semelhantes aos de séries internacionais publicadas.

Referências

Rosahl S, Bohr C, Lell M, Hamm K, Iro H. Diagnostics and therapy of vestibular schwannomas – an interdisciplinary challenge. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2017 Dec 18;16:Doc03. doi: 10.3205/cto000142.

Hitselberger WE, House WF. Classification of acoustic neuromas. Arch Otolaryngol. 1966 Sep;84(3):245-6.

Committee on hearing and equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). Otolaryngol Head Neck Surg. 1995 Sep;113(3):179-80. doi: 10.1016/S0194-5998(95)70101-X.

Hitselberger WE, House WF. Classification of acoustic neuromas. Arch Otolaryngol. 1966 Sep;84(3):245-6.

Samii M, Matthies C. Management of 1000 vestibular schwannomas (acoustic neuromas): surgical management and results with an emphasis on complications and how to avoid them. Neurosurgery. 1997 Jan;40(1):11-21; discussion 21-3. doi: 10.1097/00006123-199701000-00002.

Halliday J, Rutherford SA, McCabe MG, Evans DG. An update on the diagnosis and treatment of vestibular schwannoma. Expert Rev Neurother. 2018 Jan;18(1):29-39. doi: 10.1080/14737175.2018.1399795.

Carlson ML, Link MJ, Wanna GB, Driscoll CL. Management of Sporadic Vestibular Schwannoma. Otolaryngol Clin North Am. 2015 Jun;48(3):407-22. doi: 10.1016/j.otc.2015.02.003.

Stangerup SE, Caye-Thomasen P. Epidemiology and Natural History of Vestibular Schwannomas. Otolaryngol Clin North Am. 2012 Apr;45(2):257-68, vii. doi: 10.1016/j.otc.2011.12.008.

Matthies C, Samii M. Management of 1000 vestibular schwannomas (acoustic neuromas): clinical presentation. Neurosurgery. 1997 Jan;40(1):1-9; discussion 9-10. doi: 10.1097/00006123-199701000-00001.

Tos M, Charabi S, Thomsen J. Clinical experience with vestibular schwannomas: epidemiology, symptomatology, diagnosis, and surgical results. Eur Arch Otorhinolaryngol. 1998;255(1):1-6. doi: 10.1007/s004050050012.

Rosenberg SI. Natural history of acoustic neuromas. Laryngoscope. 2000 Apr;110(4):497-508. doi: 10.1097/00005537-200004000-00002.

Samii M, Matthies C. Management of 1000 vestibular schwannomas (acoustic neuromas): hearing function in 1000 tumor resections. Neurosurgery. 1997 Feb;40(2):248-60; discussion 260-2. doi: 10.1097/00006123-199702000-00005.

Berrettini S, Ravecca F, Russo F, Bruschini P, Sellari-Franceschini S. Some uncharacteristic clinical signs and symptoms of acoustic neuroma. J Otolaryngol. 1997 Apr;26(2):97-103.

Yanagihara N, Asai M. Sudden hearing loss induced by acoustic neuroma: significance of small tumors. Laryngoscope. 1993 Mar;103(3):308-11. doi: 10.1288/00005537-199303000-00011.

Rosenberg SI. Natural history of acoustic neuromas. Laryngoscope. 2000 Apr;110(4):497-508. doi: 10.1097/00005537-200004000-00002.

Hansasuta A, Choi CY, Gibbs IC, Soltys SG, Tse VC, Lieberson RE. et al. Multisession stereotactic radiosurgery for vestibular schwannomas: single-institution experience with 383 cases. Neurosurgery. 2011 Dec;69(6):1200-9. doi: 10.1227/NEU.0b013e318222e451.

Babu R, Sharma R, Bagley JH, Hatef J, Friedman AH, Adamson C. Vestibular schwannomas in the modern era: epidemiology, treatment trends, and disparities in management. J Neurosurg. 2013 Jul;119(1):121-30. doi: 10.3171/2013.1.JNS121370.

Hunter JB, Francis DO, O'Connell BP, Kabagambe EK, Bennett ML, Wanna GB. et al. Single institutional experience with observing 564 vestibular schwannomas: factors associated with tumor growth. Otol Neurotol. 2016 Dec;37(10):1630-1636. doi: 10.1097/MAO.0000000000001219.

Hillman TA, Chen DA, Quigley M, Arriaga MA. Acoustic tumor observation and failure to follow-up. Otolaryngol Head Neck Surg. 2010 Mar;142(3):400-4. doi: 10.1016/j.otohns.2009.10.047.

Casentini L, Fornezza U, Perini Z, Perissinotto E, Colombo F. Multisession stereotactic radiosurgery for large vestibular schwannomas. J Neurosurg. 2015 Apr;122(4):818-24. doi: 10.3171/2014.11.JNS131552.

Hansasuta A, Choi CY, Gibbs IC, Soltys SG, Tse VC, Lieberson RE. et al. Multisession stereotactic radiosurgery for vestibular schwannomas: single-institution experience with 383 cases. Neurosurgery. 2011 Dec;69(6):1200-9. doi: 10.1227/NEU.0b013e318222e451.

Suryanarayanan R, Ramsden RT, Saeed SR, Aggarwal R, King AT, Rutherford S. et al. Vestibular schwannoma: role of conservative management. J Laryngol Otol. 2010 Mar;124(3):251-7. doi: 10.1017/S0022215109992362.

Sughrue ME, Yang I, Aranda D, Lobo K, Pitts LH, Cheung SW. et al. The natural history of untreated sporadic vestibular schwannomas: a comprehensive review of hearing outcomes. J Neurosurg. 2010 Jan;112(1):163-7. doi: 10.3171/2009.4.JNS08895.

Mascarenhas F, Costa MS, Ortiz M, Almeida A, Carvalho H, Ferreira AG. et al. A radiocirurgia estereotáxica em tumores benignos e malignos do sistema nervoso central. Acta Med Port. 2005 Jan-Feb;18(1):45-60.

Kano H, Kondziolka D, Khan A, Flickinger JC, Lunsford LD. Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma. J Neurosurg. 2009 Oct;111(4):863-73. doi: 10.3171/2008.12.JNS08611.

Timmer FC, Hanssens PE, van Haren AE, Mulder JJ, Cremers CW, Beynon AJ. et al. Gamma knife radiosurgery for vestibular schwannomas: results of hearing preservation in relation to the cochlear radiation dose. Laryngoscope. 2009 Jun;119(6):1076-81. doi: 10.1002/lary.20245.

Chopra R, Kondziolka D, Niranjan A, Lunsford LD, Flickinger JC. Long-term follow-up of acoustic schwannoma radiosurgery with marginal tumor doses of 12 to 13 Gy. Int J Radiat Oncol Biol Phys. 2007 Jul 1;68(3):845-51. doi: 10.1016/j.ijrobp.2007.01.001.

Chung WY, Liu KD, Shiau CY, Wu HM, Wang LW, Guo WY. et al. Gamma knife surgery for vestibular schwannoma: 10-year experience of 195 cases. J Neurosurg. 2005 Jan;102 Suppl:87-96.

Hasegawa T, Fujitani S, Katsumata S, Kida Y, Yoshimoto M, Koike J. Stereotactic radiosurgery for vestibular schwannomas: analysis of 317 patients followed more than 5 years. Neurosurgery. 2005 Aug;57(2):257-65; discussion 257-65. doi: 10.1227/01.neu.0000166542.00512.84.

Lunsford LD, Niranjan A, Flickinger JC, Maitz A, Kondziolka D. Radiosurgery of vestibular schwannomas: summary of experience in 829 cases. J Neurosurg. 2005 Jan;102 Suppl:195-9.

Akpinar B, Mousavi SH, McDowell MM, Niranjan A, Faraji AH, Flickinger JC. et al. Early radiosurgery improves hearing preservation in vestibular schwannoma patients with normal hearing at the time of diagnosis. Int J Radiat Oncol Biol Phys. 2016 Jun 1;95(2):729-34. doi: 10.1016/j.ijrobp.2016.01.019.

Robinett ZN, Walz PC, Miles-Markley B, Moberly AC, Welling DB. Comparison of long-term quality-of-life outcomes in vestibular schwannoma patients. Otolaryngol Head Neck Surg. 2014 Jun;150(6):1024-32. doi: 10.1177/0194599814524531.

Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D. et al. EANO guideline on the diagnosis and treatment of vestibular schwannoma. Neuro Oncol. 2020 Jan 11;22(1):31-45. doi: 10.1093/neuonc/noz153.

Link MJ, Driscoll CL, Foote RL, Pollock BE. Radiation therapy and radiosurgery for vestibular schwannomas: indications, techniques, and results. Otolaryngol Clin North Am. 2012 Apr;45(2):353-66, viii-ix. doi: 10.1016/j.otc.2011.12.006.

Charabi S, Mantoni M, Tos M, Thomsen J. Cystic vestibular schwannomas: neuroimaging and growth rate. J Laryngol Otol. 1994 May;108(5):375-9. doi: 10.1017/s0022215100126854.

Nutik SL, Babb MJ. Determinants of tumor size and growth in vestibular schwannomas. J Neurosurg. 2001 Jun;94(6):922-6. doi: 10.3171/jns.2001.94.6.0922.

Vivas EX, Carlson ML, Neff BA, Shepard NT, McCracken DJ, Sweeney AD. et al. Congress of neurological surgeons systematic review and evidence-based guidelines on intraoperative cranial nerve monitoring in vestibular schwannoma surgery. Neurosurgery. 2018 Feb 1;82(2):E44-E46. doi: 10.1093/neuros/nyx513.

Barker FG 2nd, Carter BS, Ojemann RG, Jyung RW, Poe DS, McKenna MJ. Surgical excision of acoustic neuroma: patient outcome and provider caseload. Laryngoscope. 2003 Aug;113(8):1332-43. doi: 10.1097/00005537-200308000-00013.

Mangham CA Jr. Retrosigmoid versus middle fossa surgery for small vestibular schwannomas. Laryngoscope. 2004 Aug;114(8):1455-61. doi: 10.1097/00005537-200408000-00026.

Jacob JT, Carlson ML, Driscoll CL, Link MJ. Volumetric analysis of tumor control following subtotal and near-total resection of vestibular schwannoma. Laryngoscope. 2016 Aug;126(8):1877-82. doi: 10.1002/lary.25779.

Koos WT, Day JD, Matula C, Levy DI. Neurotopographic considerations in the microsurgical treatment of small acoustic neurinomas. J Neurosurg. 1998 Mar;88(3):506-12. doi: 10.3171/jns.1998.88.3.0506.

Gharabaghi A, Samii A, Koerbel A, Rosahl SK, Tatagiba M, Samii M. Preservation of function in vestibular schwannoma surgery. Neurosurgery. 2007 Feb;60(2 Suppl 1):ONS124-7; discussion ONS127-8. doi: 10.1227/01.NEU.0000249245.10182.0D.

Rabelo de Freitas M, Russo A, Sequino G, Piccirillo E, Sanna M. Analysis of hearing preservation and facial nerve function for patients undergoing vestibular schwannoma surgery: the middle cranial fossa approach versus the retrosigmoid approach—personal experience and literature review. Audiol Neurootol. 2012;17(2):71-81. doi: 10.1159/000329362.

Driscoll CL, Jackler RK, Pitts LH, Banthia V. Is the entire fundus of the internal auditory canal visible during the middle fossa approach for acoustic neuroma? Am J Otol. 2000 May;21(3):382-8. doi: 10.1016/s0196-0709(00)80048-4.

Goddard JC, Schwartz MS, Friedman RA. Fundal fluid as a predictor of hearing preservation in the middle cranial fossa approach for vestibular schwannoma. Otol Neurotol. 2010 Sep;31(7):1128-34. doi: 10.1097/MAO.0b013e3181e8fc3f.

Master AN, Roberts DS, Wilkinson EP, Slattery WH, Lekovic GP. Endoscope-assisted middle fossa craniotomy for resection of inferior vestibular nerve schwannoma extending lateral to transverse crest. Neurosurg Focus. 2018 Mar;44(3):E7. doi: 10.3171/2017.12.FOCUS17663.

Wackym PA, King WA, Poe DS, Meyer GA, Ojemann RG, Barker FG. et al. Adjunctive use of endoscopy during acoustic neuroma surgery. Laryngoscope. 1999 Aug;109(8):1193-201. doi: 10.1097/00005537-199908000-00003.

Roland JT Jr, Fishman AJ, Golfinos JG, Cohen N, Alexiades G, Jackman AH. Cranial nerve preservation in surgery for large acoustic neuromas. Skull Base. 2004 May;14(2):85-90; discussion 90-1. doi: 10.1055/s-2004-828699.

Sughrue ME, Kaur R, Rutkowski MJ, Kane AJ, Kaur G, Yang I. et al. Extent of resection and the long-term durability of vestibular schwannoma surgery. J Neurosurg. 2011 May;114(5):1218-23. doi: 10.3171/2010.11.JNS10257.

Hahn CH, Stangerup SE, Caye-Thomasen P. Residual tumour after vestibular schwannoma surgery. J Laryngol Otol. 2013 Jun;127(6):568-73. doi: 10.1017/S0022215113000844.

Bloch DC, Oghalai JS, Jackler RK, Osofsky M, Pitts LH. The fate of the tumor remnant after less-than-complete acoustic neuroma resection. Otolaryngol Head Neck Surg. 2004 Jan;130(1):104-12. doi: 10.1016/S0194-5998(03)01598-5.

Seol HJ, Kim CH, Park CK, Kim CH, Kim DG, Chung YS. et al. Optimal extent of resection in vestibular schwannoma surgery: relationship to recurrence and facial nerve preservation. Neurol Med Chir (Tokyo). 2006 Apr;46(4):176-80; discussion 180-1. doi: 10.2176/nmc.46.176.

Carlson ML, Link MJ, Driscoll CLW, Neff BA, Van Gompel JJ, Flemming KD. et al. Comprehensive Management of Vestibular Schwannoma. New York: Thieme; 2019. 593 p.

Chen CW, Young YH, Tseng HM. Preoperative versus postoperative role of vestibular-evoked myogenic potentials in cerebellopontine angle tumor. Laryngoscope. 2002 Feb;112(2):267-71. doi: 10.1097/00005537-200202000-00013.

Iwasaki S, Murofushi T, Chihara Y, Ushio M, Suzuki M, Curthoys IS. et al. Ocular vestibular evoked myogenic potentials to bone-conducted vibration in vestibular schwannomas. Otol Neurotol. 2010 Jan;31(1):147-52. doi: 10.1097/MAO.0b013e3181c0e670.

Constanzo F, Sens P, Teixeira BCA, Ramina R. Video head impulse test to preoperatively identify the nerve of origin of vestibular schwannomas. Oper Neurosurg (Hagerstown). 2019 Mar 1;16(3):319-325. doi: 10.1093/ons/opy103.

Rahne T, Plontke SK, Fröhlich L, Strauss C. Optimized preoperative determination of nerve of origin in patients with vestibular schwannoma. Sci Rep. 2021 Apr 21;11(1):8608. doi: 10.1038/s41598-021-87515-1.

Hentschel M, Scholte M, Steens S, Kunst H, Rovers M. The diagnostic accuracy of non-imaging screening protocols for vestibular schwannoma in patients with asymmetrical hearing loss and/or unilateral audiovestibular dysfunction: a diagnostic review and meta-analysis. Clin Otolaryngol. 2017 Aug;42(4):815-823. doi: 10.1111/coa.12788.

Dunn IF, Bi WL, Mukundan S, Delman BN, Parish J, Atkins T. et al. Congress of neurological surgeons systematic review and evidence-based guidelines on the role of imaging in the diagnosis and management of patients with vestibular schwannomas. Neurosurgery. 2018 Feb 1;82(2):E32-E34. doi: 10.1093/neuros/nyx510.

Carlson ML, Vivas EX, McCracken DJ, Sweeney AD, Neff BA, Shepard NT. et al. Congress of neurological surgeons systematic review and evidence-based guidelines on hearing preservation outcomes in patients with sporadic vestibular schwannomas. Neurosurgery. 2018 Feb 1;82(2):E35-E39. doi: 10.1093/neuros/nyx511.

Piccirillo E, Hiraumi H, Hamada M, Russo A, De Stefano A, Sanna M. Intraoperative cochlear nerve monitoring in vestibular schwannoma surgery—does it really affect hearing outcome? Audiol Neurootol. 2008;13(1):58-64. doi: 10.1159/000108623.

Tonn JC, Schlake HP, Goldbrunner R, Milewski C, Helms J, Roosen K. Acoustic neuroma surgery as an interdisciplinary approach: a neurosurgical series of 508 patients. J Neurol Neurosurg Psychiatry. 2000 Aug;69(2):161-6. doi: 10.1136/jnnp.69.2.161.

Publicado

18-12-2022

Como Citar

Branco, P., Colaço, T., Oliveira, J. P., Castelhano, L., Correia, F., Pereira, S., Marques, L., & Escada, P. (2022). Schwannoma vestibular: Experiência do Hospital de Egas Moniz entre 2007 e 2021. Revista Portuguesa De Otorrinolaringologia-Cirurgia De Cabeça E Pescoço, 60(4), 333–346. https://doi.org/10.34631/sporl.1045

Edição

Secção

Artigo Original